Basic Info.
Function
Antibiotic and Antimicrobial Agents, Specialist Drugs, Atopic Dermatitis
Grade Standard
Medicine Grade
Storage
Room Temperature of 2-8°C
Use
Atopic Dermatitis Treatment
Grade
Pharmaceutical Grade
Product Description
Product Description
Star products in JANUARY 2022--HyperChem |
Identification |
Name | Abrocitinib |
Other names | Abrocitinib 1622902-68-4 PF-04965842 Cibinqo N-[cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl]propane-1-sulfonamide |
CAS number | 1622902-68-4 |
Molecular Formula | |
Molecular Weight | 323.41 |
EINECS | / |
Chemical and Physical Properties |
Appearance | White Powder |
Melting Point | 208-210°C |
Boling Point | / |
Quality standard | In-house |
Application |
Drug Indication/Application | Abrocitinib is an oral small-molecule inhibitor of Janus kinase 1 (JAK1). Janus kinases are intracellular enzymes involved in transduction pathways that regulate hematopoiesis and immune cell function. The Janus kinase (JAK)-signal transducer and activator of transcription (STAT) signalling pathway plays a central role in the pathogenesis of a variety of autoimmune and inflammatory diseases, including atopic dermatitis, a chronic inflammatory skin disease with complex pathogenesis.
Atopic dermatitis is characterized by epidermal hyperplasia, skin barrier dysfunction, and the aberrant activation of immune cells. Patients with moderate-to-severe atopic dermatitis report reduced quality of life and often face limited treatment options. JAK inhibitors recently attracted more attention as potential treatments for inflammatory disorders, as JAK inhibition is associated with rapid and sustained anti-inflammatory efects.
Abrocitinib was approved by the European Commission on December 10, 2021, for the treatment of moderate-to-severe atopic dermatitis (AD) in adults who are candidates for systemic therapy. On January 14, 2022, the FDA approved abrocitinib for the treatment of refractory, moderate-to-severe AD in adults whose disease is not adequately controlled with other systemic drug products, including biologics, or when the use of those therapies is inadvisable. Health Canada also approved the use of abrocitinib in pediatric patients 12 years and older. |
Formulations/Preparations | Tablet Powder for Suspension Tablet, Chewable Tablet, Extended Release Capsule |
Handling and Storage |
Safety and Hazards | The Shanghai Research Institute of Chemical industry testing center identification conclusion :1 No hazard identification, 2 The substance is not subject to IATA DGR, 3 Nonpacking requirements. |
Handling and Storage | Store at a controlled room temperature 2-8ºC |
Sample package | Double plastic bags inside, aluminum foil bag outside |
Commercial package | Double plastic bags inside,5kg, 10kg, and 25kg fiber drum outside. |
UN Code | / |
HS Code | 29339900 |
Shipping group | Shipment at ambient temperature for no controlled and no dangerous goods |
Sales restriction | No |
Origin | China |
Technnical support |
Abrocitinib,STD Data sheet Abrocitinib,MSDS Abrocitinib,COA Abrocitinib,Transport Certificate | Yes Yes Yes Yes |
Company Profile
Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials
produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials
to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements
companies worldwide.
Workshop Display
Laboratory Display
Our Exhibition
Our Certificates
FAQ
Q1 What is the Hyper chem payment term?
T/T advance
LC at sight
DP at sight
Trade assurance
Western union
Money gram
Q2 What is Hyper chem shipment policy?
Our policy is to strive for the quickest shipment time possible, with ready stock sample shipment typically going out the same day that your order was placed. Your satisfaction is very important to us.
For non-ready stock, please contact Hyper Chem sales team to negotiate.
Q3 What hyper chem will provide after shipment?
For sample orders:
After shipment is done, an timely email including:
- Track details (Fedex /TNT/DHL/EMS Track number)
- Package photo
- COA, MSDS, etc
- Dispatch date & Estimated arriving time
- Shipping invoice
For commercial orders
A full set of shipment documents as well as package photos can be provided
in scan-copy and original, to help customers complete the customs clearance process.
Q4 What is Hyper Chem shipment term?
By Express
DHL FedEx TNT EMS
Fast:5 days around
High cost, door to door service
By-Air
Suitable for more than 50kg
Fast :3-7 days Hight cost, port to port, professional broker needed
By sea
Suitable for more than 500kg
Slow:7-45 days, Low cost, port to port, professional broker needed
We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.
Q5. Does hyper chem provide a shipment return policy?
Yes, we have.
Return Policy: At Hyper chem, your satisfaction is guaranteed. If you are dissatisfied for any reason with a product, please send back the unused portion along with your packing slip and a brief note on why you were dissatisfied within 45 days of purchase for a full refund to:
Hangzhou Hyper Chemicals Limited
No.188 Hongxing Rd,
Hangzhou,310005,
Zhejiang, China
Sorry, we cannot accept packages without postage/freight prepaid.
Q8 What is hyper chem After-sales service
Documents support: COA ,MSDS, MOA ,MS Report,HNMR Report,SDS,DMF
• Customer Support: Shipment clearance support, quality issue support
• Automated Customer Service: Our worldwide customers enjoy immediate 24/7 access to the HYPER CHEM support team from any location, at any time.
Address:
Room 803, Tower 4, Loft49 Creative City Pioneer Zone, No. 88 Jiru Road, Gongshu District, Hangzhou, Zhejiang, China
Business Type:
Manufacturer/Factory, Trading Company
Business Range:
Agriculture & Food, Chemicals, Health & Medicine, Packaging & Printing, Textile
Management System Certification:
ISO 9001, GMP
Company Introduction:
Greetings and salutations, we hope you are doing well and pray for this to continue onwards. Allow us to introduce ourselves. We are Hangzhou Hyper Chemicals Limited, an international supplier of pharmaceutical raw materials. Experts in providing raw materials, resources, customized manufacturing, and much more.
We especially provide ourselves with the supplying of high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients. Among them, our key client industrial sectors around the globe are:
Pharmaceuticals:
Nutrition ingredients/ Dietary supplements
Cosmetic Ingredients:
Veterinary Drug
Agriculture fertilizer
Custom Synthesis lab supply
HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation. We are trusted by big names who trust us in providing them with world-class and top-quality products.